Direct Etherification of Alkyl Halides by Sodium Hydride in the Presence of N,N-Dimethylformamide Direct Etherification of Alkyl Halides

نویسندگان

  • Cheng Hua Jin
  • Ho Young Lee
  • Sang Hwi Lee
  • In Su Kim
  • Young Hoon Jung
چکیده

SYNLETT 2007, No. 17, pp 2695–269816.10.2007 Advanced online publication: 25.09.2007 DOI: 10.1055/s-2007-991068; Art ID: U07007ST © Georg Thieme Verlag Stuttgart · New York Abstract: A novel synthetic method for the preparation of various alkyl ethers is described. The reaction between alkyl halides and sodium hydride in the presence of N,N-dimethylformamide afforded the corresponding symmetrical and unsymmetrical ethers in high yields. A reaction mechanism for etherification is also proposed.

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تاریخ انتشار 2007